RESUMO
INTRODUCTION:: Emerging diseases are of great interest, especially those associated with high mortality rates such as hantaviruses. We aimed to conduct a seroepidemiological survey to determine the levels of hantavirus infection. METHODS:: In-house enzyme-linked immunosorbent assay (ELISA) was used to detect specific antibodies. RESULTS:: Of the 429 samples collected, seropositivity of 3.9% to anti-hantavirus immunoglobulin G (IgG) was observed (CI 95%: 2.3-5.7). Moreover, in three cases, immunoglobulin M (IgM) was detected, of which two were diagnosed as hantavirus cardiopulmonary syndrome (HCPS). CONCLUSIONS:: Our data indicate the considerable occurrence of previous hantavirus infections, highlighting occurrences from sub-clinical cases to HCPS.
Assuntos
Anticorpos Antivirais/sangue , Infecções por Hantavirus/epidemiologia , Orthohantavírus/imunologia , Adulto , Brasil/epidemiologia , Criança , Ensaio de Imunoadsorção Enzimática , Feminino , Infecções por Hantavirus/diagnóstico , Humanos , Imunoglobulina G/sangue , Imunoglobulina M/sangue , Masculino , Pessoa de Meia-Idade , População Rural , Estudos Soroepidemiológicos , Adulto JovemRESUMO
Abstract INTRODUCTION: Emerging diseases are of great interest, especially those associated with high mortality rates such as hantaviruses. We aimed to conduct a seroepidemiological survey to determine the levels of hantavirus infection. METHODS: In-house enzyme-linked immunosorbent assay (ELISA) was used to detect specific antibodies. RESULTS: Of the 429 samples collected, seropositivity of 3.9% to anti-hantavirus immunoglobulin G (IgG) was observed (CI 95%: 2.3-5.7). Moreover, in three cases, immunoglobulin M (IgM) was detected, of which two were diagnosed as hantavirus cardiopulmonary syndrome (HCPS). CONCLUSIONS: Our data indicate the considerable occurrence of previous hantavirus infections, highlighting occurrences from sub-clinical cases to HCPS.
Assuntos
Humanos , Masculino , Feminino , Criança , Adulto , Adulto Jovem , Orthohantavírus/imunologia , Infecções por Hantavirus/epidemiologia , Anticorpos Antivirais/sangue , População Rural , Brasil/epidemiologia , Imunoglobulina G/sangue , Imunoglobulina M/sangue , Ensaio de Imunoadsorção Enzimática , Estudos Soroepidemiológicos , Infecções por Hantavirus/diagnóstico , Pessoa de Meia-IdadeRESUMO
Infection with hantavirus, from the family Bunyaviridae, causes hantavirus cardiopulmonary syndrome (HCPS) in the Americas. This highly lethal anthropozoonosis afflicts preferentially individuals in rural areas and is transmitted by aerosol of excreta from infected wild rodents. The aim of this study is to report the almost simultaneous occurrence of two cases of HCPS in the municipality of Jataí, state of Goiás, Brazil.
A infecção por hantavírus, família Bunyaviridae, provoca a síndrome cardiopulmonar por hantavírus (SCPH) nos países da América. Ela é uma antropozoonose, de elevada letalidade, que tem acometido preferencialmente indivíduos em contato com o meio rural, sendo transmitida por aerossóis a partir das excretas dos roedores silvestres infectados. O objetivo deste estudo foi relatar a ocorrência, quase que simultânea, de dois casos de SCPH ocorridos no município de Jataí, Estado de Goiás, Brasil.
